Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 4/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200544 | 0.90 | ALDH1A1 (0.50) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL3369180 | 0.87 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL2196957 | 0.84 | MAPK14 (0.46) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2573776 | 0.81 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2198854 | 0.80 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2195432 | 0.80 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2574934 | 0.79 | MAPK14 (0.44) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2196799 | 0.79 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL2198654 | 0.79 | MAPK14 (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2199579 | 0.78 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658263-B9 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2011-11-09 | — | — | EP | claimed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | claimed |
| EP-1658263-B9 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2011-11-09 | — | — | EP | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |