Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574934 | 0.88 | MAPK14 (0.44) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2200544 | 0.87 | ALDH1A1 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2572688 | 0.86 | MAPK14 (0.47) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL3369180 | 0.85 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2196799 | 0.82 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2196957 | 0.81 | MAPK14 (0.46) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2201902 | 0.81 | MAPK14 (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2198654 | 0.81 | MAPK14 (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2199579 | 0.81 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2196964 | 0.81 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658263-B9 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2011-11-09 | — | — | EP | claimed |
| EP-1658263-B1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-06-02 | — | — | EP | claimed |