Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LONP1 | P36776 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21968829 | 1.00 | FPR1 (0.56) | FPR1ALDH1A1USP2TP53ALOX15 | |
| SCHEMBL9830718 | 0.85 | LONP1 (0.63) | LONP1CTSL | |
| SCHEMBL9830710 | 0.85 | LONP1 (0.63) | LONP1CTSL | |
| SCHEMBL26471826 | 0.83 | LONP1 (0.51) | LONP1CTSLCA2CA1 | |
| SCHEMBL2328038 | 0.82 | KMT2A (0.55) | ALDH1A1USP2TP53ALOX15MAPK1 | |
| SCHEMBL2328043 | 0.82 | KMT2A (0.55) | ALDH1A1USP2TP53ALOX15MAPK1 | |
| SCHEMBL21968319 | 0.81 | FPR1 (0.48) | FPR1ALDH1A1LONP1CTSL | |
| SCHEMBL21968836 | 0.81 | FPR1 (0.48) | FPR1ALDH1A1LONP1CTSL | |
| SCHEMBL22610052 | 0.80 | LONP1 (0.51) | ALDH1A1ALOX15LONP1CTSLCA2 | |
| SCHEMBL22610053 | 0.80 | LONP1 (0.51) | ALDH1A1ALOX15LONP1CTSLCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159471-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-11584725-B2 | Pyrazinoic acid conjugates and hybrid conjugates | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200140397-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584725-B2 | Pyrazinoic acid conjugates and hybrid conjugates | QPCT, RARA, PNKP | FPR1 238/4885ALDH1A1 240/4885USP2 3715/4885 |
| US-20200140397-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | QPCT, RARA, PNKP | FPR1 238/4885ALDH1A1 240/4885USP2 3715/4885 |
| US-20230159471-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | QPCT, RARA, PNKP | FPR1 238/4885ALDH1A1 240/4885USP2 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.