Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21973053 | 0.87 | IMPDH1 (0.39) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL21973054 | 0.86 | CYP3A4 (0.33) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL21972847 | 0.85 | CYP3A4 (0.33) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL21973049 | 0.73 | IMPDH1 (0.35) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL21972842 | 0.72 | FNTA (0.34) | CYP3A4 | |
| SCHEMBL21973051 | 0.72 | ALOX5 (0.34) | — | |
| SCHEMBL21973223 | 0.70 | — | — | |
| SCHEMBL6200978 | 0.62 | CYP3A4 (0.53) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL8684158 | 0.59 | CYP3A4 (0.57) | CYP3A4TOP2APDE1APDE1BPDE3B | |
| SCHEMBL21973052 | 0.58 | POLB (0.46) | CYP3A4PDE1APDE1BPDE3BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140450-A1 | CHEMICAL METHOD OF PRODUCING SMTP GROUPS OR SMTP-7 AND INTERMEDIATES USED IN THE METHOD | SHOWA UNIVERSITY (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140450-A1 | CHEMICAL METHOD OF PRODUCING SMTP GROUPS OR SMTP-7 AND INTERMEDIATES USED IN THE METHOD | TST, SMS, TMSB4X | CYP3A4 276/4885TOP2A 1484/4885PDE1A 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.