Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | APOL1 | O14791 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20495025 | 0.99 | SCN9A (0.34) | SCN9ACNR2TDO2DPP4CHEK2 | |
| Hydrochloric Acid SCHEMBL20495029 | 0.99 | SCN9A (0.34) | SCN9ACNR2TDO2DPP4CHEK2 | |
| SCHEMBL21973163 | 0.88 | ULK1 (0.35) | CHEK2FLT3ULK1 | |
| SCHEMBL21973146 | 0.88 | ULK1 (0.35) | CHEK2FLT3ULK1 | |
| Hydrochloric Acid SCHEMBL20495257 | 0.87 | ULK1 (0.34) | CHEK2FLT3ULK1 | |
| Hydrochloric Acid SCHEMBL20495259 | 0.87 | ULK1 (0.34) | CHEK2FLT3ULK1 | |
| SCHEMBL21973143 | 0.86 | FAAH (0.36) | SCN9ACNR2CHEK2FLT3ABL1 | |
| SCHEMBL21973439 | 0.86 | FAAH (0.36) | SCN9ACNR2CHEK2FLT3ABL1 | |
| Hydrochloric Acid SCHEMBL20495069 | 0.85 | FAAH (0.36) | SCN9ACNR2CHEK2FLT3ABL1 | |
| Hydrochloric Acid SCHEMBL20494979 | 0.85 | FAAH (0.36) | SCN9ACNR2CHEK2FLT3ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180459-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200140393-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180459-B2 | Bacterial efflux pump inhibitors | ABCB11, ABCB1, SLC47A1 | SCN9A 1528/4885CNR2 4493/4885TDO2 1813/4885 |
| US-20200140393-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | SCN9A 1528/4885CNR2 4493/4885TDO2 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.