Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875639 | 0.77 | KDM1A (0.43) | KLK7OPRD1OPRK1OPRM1WDR5 | |
| SCHEMBL16021609 | 0.74 | SOAT2 (0.43) | — | |
| SCHEMBL3124456 | 0.74 | GAA (0.51) | — | |
| SCHEMBL17867151 | 0.74 | GAA (0.51) | — | |
| SCHEMBL2864427 | 0.74 | GAA (0.51) | — | |
| SCHEMBL22916085 | 0.74 | OPRM1 (0.42) | OPRD1OPRK1OPRM1 | |
| SCHEMBL13507255 | 0.72 | OPRK1 (0.49) | KLK7OPRD1OPRK1OPRM1 | |
| SCHEMBL21973546 | 0.72 | KEAP1 (0.42) | OPRD1OPRK1OPRM1KEAP1 | |
| SCHEMBL16023827 | 0.72 | KEAP1 (0.42) | OPRD1OPRK1OPRM1KEAP1 | |
| SCHEMBL21973224 | 0.71 | TEAD4 (0.44) | KLK7OPRD1OPRK1OPRM1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024476-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2021-01-28 | — | — | US | disclosed |
| US-20180170889-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024476-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | AIP, AIPL1, CGAS | KLK7 3376/4885OPRD1 4315/4885OPRK1 3584/4885 |
| US-20180170889-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | AIP, AIPL1, CGAS | KLK7 3376/4885OPRD1 4315/4885OPRK1 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.