Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317376 | 0.83 | HSD17B10 (0.47) | CYP2A6ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL18317373 | 0.83 | HPRT1 (0.56) | CYP2A6ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL2117384 | 0.80 | ALDH1A1 (0.38) | CYP2A6ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL1557072 | 0.79 | ALDH1A1 (0.37) | CYP2A6ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL114219 | 0.75 | ALDH1A1 (0.48) | CYP2A6ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL1178290 | 0.74 | — | — | |
| SCHEMBL7762823 | 0.73 | DHFR (0.47) | CYP2A6ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL1535589 | 0.73 | CYP1A2 (0.47) | CYP2A6ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL2254086 | 0.73 | — | — | |
| SCHEMBL3895040 | 0.73 | ALDH1A1 (0.43) | CYP2A6ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | claimed |
| CN-109734666-B | Preparation method for synthesizing indazolinones compound by carbon dioxide promotion and photo-induction without photocatalyst | 湖南大学 | 2023-03-28 | — | — | CN | claimed |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | claimed |
| EP-3898588-B1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-01-11 | — | — | EP | claimed |
| WO-2021249969-A1 | COMBINATION PRODUCT FOR THE TREATMENT OF CANCER DISEASES | MERCK PATENT GMBH (DE) | 2021-12-16 | — | — | WO | claimed |
| EP-3898588-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | Merck Patent GmbH (DE) | 2021-10-27 | — | — | EP | claimed |
| EP-3625228-B1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-07 | — | — | EP | claimed |
| US-20210113559-A1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-04-22 | — | — | US | claimed |
| CN-107602609-B | Method for preparing organic phosphate compound by using P (O) -OH compound and methyl-containing substituted aromatic hydrocarbon | 湖南理工学院 | 2020-07-21 | — | — | CN | claimed |
| WO-2020127960-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | claimed |
| CN-1080916-A | The quinic tricyclic compound of anti-column foot, its preparation method and contain the pharmaceutical composition of this compound | MENARINI FARMA IND (IT) | 1994-01-19 | — | — | CN | claimed |
| WO-1993021227-A1 | TACHYKININ ANTAGONIST TRICYCLIC COMPOUNDS, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1993-10-28 | — | — | WO | claimed |
| EP-0325266-B1 | DENTAL MATTER | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0278543-B1 | PROCESS AND COMPOSITION FOR INHIBITING HIGH-TEMPERATURE IRON AND STEEL CORROSION | PUMPTECH N.V. (BE) | 1992-09-23 | — | — | EP | claimed |
| EP-0325266-A2 | Dental matter | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1989-07-26 | — | — | EP | claimed |
| EP-0184095-B1 | BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1989-07-05 | — | — | EP | claimed |
| US-4737593-A | PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY | Fabrik Pharmazeutischer Praparate (DE) | 1988-04-12 | — | — | US | claimed |
| EP-0184095-A2 | Bisacylphosphinoxides, their preparation and use | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1986-06-11 | — | — | EP | claimed |
| US-4174222-A | NAPHTHOQUINONE-(1,2)-DIAZIDO-(2)-SULFONIC ACID ESTER OF ALKYL OR ARYL GALLATE, PHENOLIC NOVOLAC RESIN TO GIVE ETCH RESISTANCE | TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) | 1979-11-13 | — | — | US | claimed |
| US-4101690-A | COLOR DEVELOPERS, ETHYLENE OXIDE-PROPYLENE OXIDE-AMINE ADDUCTS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-07-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | CYP2A6 131/4885ALDH1A1 468/4885TSHR 654/4885 |
| US-20210113559-A1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER1, PTGER4, PTGER2 | CYP2A6 131/4885ALDH1A1 468/4885TSHR 654/4885 |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | BRCA1, MYC, PCNA | CYP2A6 2603/4885ALDH1A1 414/4885TSHR 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.