SCHEMBL2197571

SCHEMBL2197571

C=C(C)C(=O)NCCN1CCN(C(=O)C(=C)C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.33
KDM4E B2RXH2 1/20 0.32
RAB9A P51151 1/20 0.31
MTNR1A P48039 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9162992 0.82 KMT2A (0.36) KMT2ANPC1RAB9AMTNR1A
SCHEMBL4191160 0.77 CSF1R (0.34)
SCHEMBL2197563 0.76 ALDH1A1 (0.33) KMT2ANPC1
SCHEMBL4184795 0.74 TDP1 (0.32)
SCHEMBL166209 0.74 KMT2A (0.56) KMT2AKDM4ERAB9A
SCHEMBL19145900 0.74 KMT2A (0.64) KMT2ANPC1RAB9A
SCHEMBL8508945 0.73
SCHEMBL2197438 0.72 KMT2A (0.44) KMT2ANPC1KDM4ERAB9A
SCHEMBL8735006 0.72 NPSR1 (0.35) KMT2AKDM4E
SCHEMBL19145899 0.71 KMT2A (0.57) KMT2ANPC1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773760-B1 CATALYTIC METHODS FOR THE PRODUCTION OF (METH)ACRYLATES FROM N-HYDROXYALKYLATED AMIDES BASF SE (DE) 2017-01-11 EP disclosed
US-8263371-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2012-09-11 US disclosed
US-7993886-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSHAFT (DE) 2011-08-09 US disclosed
US-20110171697-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSHAFT (DE) 2011-07-14 US disclosed
US-20100285542-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSHAFT (DE) 2010-11-11 US disclosed
US-7816485-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2010-10-19 US disclosed
EP-1773760-A1 CATALYTIC METHODS FOR THE PRODUCTION OF (METH)ACRYLATES FROM N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-04-18 EP disclosed
US-20060036063-A1 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 US disclosed
WO-2006012980-A1 CATALYTIC METHODS FOR THE PRODUCTION OF (METH)ACRYLATES FROM N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSCHAFT (DE) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285542-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES NAAA, APEH, NAA15 KMT2A 518/4885NPC1 4145/4885KDM4E 1449/4885
US-20110171697-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES NAAA, APEH, NAA15 KMT2A 518/4885NPC1 4145/4885KDM4E 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.