Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102264 | 0.79 | S1PR2 (0.32) | PKLR | |
| SCHEMBL21976803 | 0.79 | PKLR (0.32) | PKLR | |
| SCHEMBL16049726 | 0.74 | — | — | |
| SCHEMBL21976838 | 0.70 | OPRM1 (0.35) | — | |
| SCHEMBL20411474 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL21976648 | 0.68 | OPRM1 (0.32) | — | |
| SCHEMBL21976465 | 0.68 | OPRM1 (0.36) | PKLR | |
| SCHEMBL8372902 | 0.68 | KMT2A (0.34) | — | |
| SCHEMBL3436780 | 0.68 | NPSR1 (0.33) | — | |
| SCHEMBL10644215 | 0.67 | NPSR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970189-B1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |