Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976469 | 0.80 | HDAC6 (0.47) | ALOX5HDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL21976229 | 0.78 | GAA (0.46) | ALOX5HDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL21976956 | 0.76 | USP2 (0.46) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL21976480 | 0.76 | HDAC6 (0.50) | ALOX5HDAC1HDAC6ARHDAC2 | |
| SCHEMBL5079028 | 0.74 | IDO1 (0.55) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL5082100 | 0.74 | IDO1 (0.55) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL21976208 | 0.72 | PBRM1 (0.44) | ALOX5HDAC1HDAC6HDAC8 | |
| SCHEMBL21976232 | 0.72 | SMPD1 (0.45) | HDAC1HDAC6HDAC2HDAC8GAA | |
| SCHEMBL10246978 | 0.71 | KDM4E (0.44) | HDAC1HDAC6CCR2HDAC2HDAC3 | |
| SCHEMBL10247090 | 0.71 | HDAC8 (0.48) | HDAC1HDAC6CCR2HDAC8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294715-B1 | BENZIMIDAZOLE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY | KANCERA AB (SE) | 2020-05-06 | — | — | EP | disclosed |