Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976900 | 0.88 | MTNR1A (0.43) | MTNR1AMTNR1BMAPTELANETSHR | |
| SCHEMBL21976734 | 0.87 | PPARG (0.46) | TSHR | |
| SCHEMBL21976759 | 0.87 | LMNA (0.46) | MTNR1AMTNR1BMAPTLMNAL3MBTL1 | |
| SCHEMBL21976920 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BMAPTELANETSHR | |
| SCHEMBL21976703 | 0.84 | ALDH1A1 (0.44) | MTNR1AMTNR1BMAPTALDH1A1MEN1 | |
| SCHEMBL17901361 | 0.82 | MAPT (0.45) | MTNR1AMTNR1BMAPTTSHRCYP1A2 | |
| SCHEMBL21976898 | 0.82 | MAPT (0.42) | MTNR1AMTNR1BMAPTELANETSHR | |
| SCHEMBL17901110 | 0.82 | MAPT (0.45) | MTNR1AMTNR1BMAPTTSHRCYP1A2 | |
| SCHEMBL17901317 | 0.82 | MAPT (0.45) | MTNR1AMTNR1BMAPTTSHRCYP1A2 | |
| SCHEMBL17901314 | 0.82 | MAPT (0.45) | MTNR1AMTNR1BMAPTTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |