Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197459 | 0.89 | SMN1; SMN2 (0.45) | ADRB3ADRB1ADRB2KCNA5SMN1; SMN2 | |
| SCHEMBL2199316 | 0.88 | CYP11B1 (0.45) | ADRB3ADRB1ADRB2KCNA5KCNH2 | |
| SCHEMBL2197465 | 0.87 | TDP1 (0.44) | ADRB3ADRB1ADRB2SMN1; SMN2 | |
| SCHEMBL2198684 | 0.84 | ADRB3 (0.41) | ADRB3ADRB1ADRB2SMN1; SMN2 | |
| SCHEMBL2194591 | 0.84 | KCNA5 (0.50) | KCNA5KCNH2FAAHCYP3A4CYP2C9 | |
| SCHEMBL2197414 | 0.84 | KCNH2 (0.42) | ADRB3ADRB1ADRB2KCNA5KCNH2 | |
| SCHEMBL2198006 | 0.82 | MAPT (0.45) | ADRB3ADRB1KCNA5FFAR1SMN1; SMN2 | |
| SCHEMBL2259742 | 0.79 | MAPT (0.43) | ADRB3ADRB1KCNA5SMN1; SMN2GPR132 | |
| SCHEMBL5320134 | 0.78 | MEN1 (0.40) | ADRB3ADRB1ADRB2KCNA5KCNH2 | |
| SCHEMBL2196293 | 0.78 | BRD4 (0.38) | ADRB3ADRB1ADRB2KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-7998983-B2 | 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethysilylisoxazole; crop protection agents to combat or prevent fungal infestations, or to control other pests such as weeds, insects, or acarids | SYNGENTA LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-7998983-B2 | 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethysilylisoxazole; crop protection agents to combat or prevent fungal infestations, or to control other pests such as weeds, insects, or acarids | SYNGENTA LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-7998983-B2 | 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethysilylisoxazole; crop protection agents to combat or prevent fungal infestations, or to control other pests such as weeds, insects, or acarids | SYNGENTA LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-20100179059-A1 | Fungicidal Mixtures | BASF SE (DE) | 2010-07-15 | — | — | US | disclosed |
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2008-07-10 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| EP-1794167-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | Syngenta Limited (GB) | 2007-06-13 | — | — | EP | disclosed |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2006-04-06 | — | — | US | disclosed |
| WO-2006031631-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | CYP4X1, CYP51A1, CYP3A7 | ADRB3 1906/4885ADRB1 2900/4885ADRB2 2997/4885 |
| US-20100179059-A1 | Fungicidal Mixtures | ARSA, AADAC, TYR | ADRB3 958/4885ADRB1 1089/4885ADRB2 2217/4885 |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | ADRB3 1952/4885ADRB1 2779/4885ADRB2 2929/4885 |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | CYP4Z1, CYP4X1, AGXT | ADRB3 1026/4885ADRB1 779/4885ADRB2 693/4885 |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | CYP4X1, CYP51A1, CYP3A7 | ADRB3 2136/4885ADRB1 2986/4885ADRB2 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.