SCHEMBL21976969

SCHEMBL21976969

CC(C)N1C(=O)c2ccc(O)cc2C1=O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.55
DPP4 P27487 3/20 0.55
ESR1 P03372 11/20 0.55
ESR2 Q92731 7/20 0.55
MAOA P21397 1/20 0.52
UGT1A1 P22309 1/20 0.52
MAOB P27338 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
APP P05067 1/20 0.44
CYP2D6 P10635 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10914223 0.82 ANPEP (0.50) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL24710720 0.82 ANPEP (0.51) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL6307015 0.81 MEN1 (0.56) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL6307012 0.81 MEN1 (0.56) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL1686814 0.81 ESR1 (0.50) ESR1ESR2MEN1KMT2AAPP
SCHEMBL17300647 0.79 BCL2 (0.41) ANPEPDPP4MEN1KMT2ATDP1
SCHEMBL6308700 0.79 ESR1 (0.48) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL6308693 0.79 ESR1 (0.48) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL317136 0.79 MEN1 (0.53) ANPEPDPP4ESR1ESR2MAOA
SCHEMBL2665475 0.78 MAOA (0.50) MAOAMAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732133-B2 Process for producing a three-dimensional object EOS GMBH ELECTRO OPTICAL SYSTEMS (DE) 2023-08-22 US disclosed
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2020-06-04 US disclosed
US-20200140706-A1 PROCESS FOR PRODUCING A THREE-DIMENSIONAL OBJECT EOS GMBH ELECTRO OPTICAL SYSTEMS (DE) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES CBR3, CBR1, CYP4X1 ANPEP 3938/4885DPP4 924/4885ESR1 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.