SCHEMBL317136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL316315	0.83	MEN1 (0.43)	MEN1KMT2AESR1ESR2CYP2D6
	SCHEMBL8330397	0.82	LMNA (0.51)	CYP2D6TDP1POLB
	SCHEMBL316573	0.82	LMNA (0.51)	CYP2D6TDP1POLB
	SCHEMBL30353214	0.81	LMNA (0.50)	CYP2D6TDP1POLB
	SCHEMBL21976969	0.79	ANPEP (0.55)	MEN1KMT2AESR1ESR2CYP2D6
	SCHEMBL315870	0.77	POLB (0.50)	KMT2APOLBMAOAMAOB
	SCHEMBL10068087	0.76	L3MBTL1 (0.49)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL3024023	0.73	APP (0.66)	MEN1KMT2AESR1ESR2ANPEP
	SCHEMBL6307012	0.72	MEN1 (0.56)	MEN1KMT2AESR1ESR2CYP2D6
	SCHEMBL6307015	0.72	MEN1 (0.56)	MEN1KMT2AESR1ESR2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.