SCHEMBL219785

SCHEMBL219785

NNC(=O)C1(C(=O)NN)CCCCC1.NNC(=O)CCCCC(=O)NN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 1/20 0.40
CTSD P07339 1/20 0.38
KDM4E B2RXH2 1/20 0.38
KDM5C P41229 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.33
DGAT1 O75907 1/20 0.33
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
CACNA2D1 P54289 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL897240 0.84 DGAT1 (0.43) ALDH1A1MAPTSMN1; SMN2DGAT1USP2
SCHEMBL28219205 0.74 ALDH1A1 (0.62) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL49856 0.74 ALDH1A1 (0.62) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL5522879 0.74 DGAT1 (0.39) ALDH1A1SMN1; SMN2DGAT1USP2LMNA
SCHEMBL27801303 0.72 DGAT1 (0.48) DGAT1LMNACYP1A2TSHR
SCHEMBL466559 0.72 ALDH1A1 (0.67) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL9007204 0.72 ALDH1A1 (0.60) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL10396767 0.72 ALDH1A1 (0.67) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL219713 0.72 ALDH1A1 (0.67) ALDH1A1MAPTGAACTSDKDM4E
SCHEMBL1630195 0.72 ALDH1A1 (0.60) ALDH1A1MAPTGAACTSDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11952505-B1 One component self-crosslinking coatings SWIMC LLC (US) 2024-04-09 US disclosed
US-11572489-B1 One component self-crosslinking coatings SWIMC LLC (US) 2023-02-07 US disclosed
EP-1851259-B1 AQUEOUS DISPERSIONS OF POLYURETHANE COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2018-04-11 EP disclosed
US-8901244-B2 Aqueous dispersions of polyurethane/acrylic hybrid compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-12-02 US disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
EP-2210908-A1 Aqueous dispersions of polyurethane compositions with ketone-hydrazide Lubrizol Advanced Materials, Inc. (US) 2010-07-28 EP disclosed
US-7576157-B2 Aqueous dispersions of polyurethane compositions with ketone-hydrazide LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-08-18 US disclosed
US-20090137734-A1 Aqueous Dispersions Of Polyurethane/Acrylic Hybrid Compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-05-28 US disclosed
EP-2046853-A1 AQUEOUS DISPERSIONS OF POLYURETHANE COMPOSITIONS WITH KETONE-HYDRAZIDE Lubrizol Advanced Materials, Inc. (US) 2009-04-15 EP disclosed
US-7476705-B2 Aqueous dispersions of polyurethane compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-01-13 US disclosed
WO-2008016843-A1 AQUEOUS DISPERSIONS OF POLYURETHANE COMPOSITIONS WITH KETONE-HYDRAZIDE LUBRIZOL ADVANCED MATERIALS, INC. (US) 2008-02-07 WO disclosed
US-20080027168-A1 Aqueous Dispersions Of Polyurethane Compositions With Ketone-Hydrazide LUBRIZOL ADVANCED MATERIALS, INC. (US) 2008-01-31 US disclosed
EP-1851259-A1 AQUEOUS DISPERSIONS OF POLYURETHANE COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2007-11-07 EP disclosed
WO-2007103542-A1 INKJET INK SET E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-09-13 WO disclosed
US-20070211126-A1 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY 2007-09-13 US disclosed
US-20060264568-A1 Aqueous Dispersions Of Polyurethane Compositions NOVEON, INC. (US) 2006-11-23 US disclosed
WO-2006086322-A1 AQUEOUS DISPERSIONS OF POLYURETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2006-08-17 WO disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed