Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738998 | 0.81 | HTR1A (0.51) | LMNATSHRALDH1A1MAPTHTR7 | |
| SCHEMBL2739000 | 0.76 | MEN1 (0.51) | LMNATSHRNPSR1ALDH1A1MAPT | |
| SCHEMBL220410 | 0.76 | HTR1A (0.58) | LMNAALDH1A1MAPTHTR7SMN1; SMN2 | |
| SCHEMBL219990 | 0.75 | KDM4E (0.41) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL219788 | 0.75 | ALDH1A1 (0.54) | LMNATSHRNPSR1ALDH1A1MAPT | |
| SCHEMBL2738999 | 0.72 | MAPT (0.53) | LMNATSHRALDH1A1MAPTHTR7 | |
| SCHEMBL217564 | 0.72 | ALDH1A1 (0.46) | LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL916036 | 0.71 | HPGD (0.38) | LMNATSHRRECQLALDH1A1RAB9A | |
| SCHEMBL30767206 | 0.71 | TSHR (0.57) | LMNATSHRNPSR1MAPK1RECQL | |
| SCHEMBL29204363 | 0.71 | TSHR (0.57) | LMNATSHRNPSR1MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |