Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738999 | 0.84 | MAPT (0.53) | ALDH1A1KCNH2MAPTLMNATSHR | |
| SCHEMBL2739004 | 0.76 | MAPT (0.54) | ALDH1A1KCNH2MAPTLMNATSHR | |
| SCHEMBL11100857 | 0.76 | ALDH1A1 (0.75) | ALDH1A1KCNH2MAPTLMNASMN1; SMN2 | |
| SCHEMBL6714846 | 0.76 | ALDH1A1 (0.75) | ALDH1A1KCNH2MAPTLMNASMN1; SMN2 | |
| SCHEMBL220410 | 0.76 | HTR1A (0.58) | ALDH1A1KCNH2MAPTLMNASMN1; SMN2 | |
| SCHEMBL2738998 | 0.76 | HTR1A (0.51) | ALDH1A1KCNH2MAPTLMNATSHR | |
| SCHEMBL219789 | 0.75 | LMNA (0.49) | ALDH1A1MAPTLMNATSHRRAB9A | |
| SCHEMBL10294634 | 0.74 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL8928315 | 0.73 | TP53 (0.48) | TSHR | |
| SCHEMBL13575585 | 0.73 | TP53 (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |