Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20690721 | 0.94 | ALDH1A1 (0.52) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL19993934 | 0.76 | ALDH1A1 (0.65) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL14945134 | 0.70 | ALDH1A1 (0.60) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL16643779 | 0.70 | ALDH1A1 (0.60) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL16643982 | 0.69 | ALDH1A1 (0.60) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL18909848 | 0.69 | ALDH1A1 (0.58) | ALDH1A1HPGDTSHRPKMSMN1; SMN2 | |
| SCHEMBL28345598 | 0.69 | CNR1 (0.41) | ALDH1A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL21640164 | 0.68 | EPHX1 (0.50) | SMN1; SMN2 | |
| SCHEMBL23421378 | 0.67 | ABCB1 (0.40) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL1093850 | 0.67 | NR1H2 (0.53) | ALDH1A1HPGDSMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660023-B1 | THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2023-03-08 | — | — | EP | disclosed |
| CN-110959007-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-109305976-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-11186587-B2 | Compound as ACC inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2021-11-30 | — | — | US | disclosed |
| EP-3660023-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2020-06-03 | — | — | EP | disclosed |
| US-20200165265-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
| CN-110959007-A | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2020-04-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165265-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | ACACA, ACACB, ACAT2 | ALDH1A1 87/4885HPGD 390/4885TSHR 4515/4885 |
| US-11186587-B2 | Compound as ACC inhibitor and use thereof | ACACA, ACACB, ACAT2 | ALDH1A1 87/4885HPGD 390/4885TSHR 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.