Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202965 | 0.74 | KDM4E (0.56) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL13916682 | 0.74 | KDM4E (0.69) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL13916685 | 0.72 | KDM4E (0.67) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL843785 | 0.70 | PDGFRB (0.65) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL6200577 | 0.70 | PDGFRB (0.65) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL844287 | 0.67 | PDGFRB (1.00) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL844223 | 0.67 | PDGFRB (1.00) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL27306910 | 0.65 | ALDH1A1 (0.53) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL862261 | 0.65 | KDM4E (0.62) | PDGFRBKITFLT3KDM4EALDH1A1 | |
| SCHEMBL14871089 | 0.64 | KDM4E (0.52) | PDGFRBKITFLT3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712419-B2 | Liposome formulations | OPKO PHARMACEUTICALS, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-20200163877-A1 | LIPOSOME FORMULATIONS | OPKO PHARMACEUTICALS, LLC. | 2020-05-28 | — | — | US | disclosed |