SCHEMBL21980910

SCHEMBL21980910

N#Cc1cc(C(=O)O)c(C(F)(F)F)nc1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 0.46
TAS2R14 Q9NYV8 1/20 0.44
KDM4E B2RXH2 3/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM5A P29375 1/20 0.39
KIF11 P52732 2/20 0.39
MAPT P10636 2/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK1 P28482 2/20 0.38
MAP2K4 P45985 2/20 0.38
MAPK6 Q16659 2/20 0.38
MAPKAPK3 Q16644 1/20 0.38
MAPKAPK5 Q8IW41 1/20 0.38
DHODH Q02127 2/20 0.38
GSR P00390 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30670339 0.86 XDH (0.53) XDHTAS2R14KDM4EHTTSMN1; SMN2
SCHEMBL24688774 0.86 XDH (0.53) XDHTAS2R14KDM4EHTTSMN1; SMN2
SCHEMBL19601275 0.84 XDH (0.43) XDHTAS2R14KDM4EHTTSMN1; SMN2
SCHEMBL22035964 0.80 KCNH2 (0.48) KDM4EALDH1A1KDM1A
SCHEMBL30670336 0.79 XDH (0.48) XDHTAS2R14KDM4EHTTSMN1; SMN2
SCHEMBL23120425 0.76 KDM4E (0.40) TAS2R14KDM4EMAPTALDH1A1HSD17B10
SCHEMBL21980906 0.76 ALDH1A1 (0.46) KDM4EHTTSMN1; SMN2ALDH1A1
SCHEMBL21980897 0.76 GPR119 (0.47) KDM4EMAPTPOLBALDH1A1
SCHEMBL22036424 0.76 ALDH1A1 (0.54) KDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL5062114 0.75 KHK (0.41) TAS2R14KDM4ESMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622969-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-10-01 EP disclosed
WO-2024110215-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-05-30 WO disclosed
EP-3889137-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2021-10-06 EP disclosed
EP-3674291-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2020-07-01 EP disclosed
US-20200163336-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2020-05-28 US disclosed
US-20200163336-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163336-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT H1-10, TAAR1, C5 XDH 3707/4885TAS2R14 394/4885KDM4E 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.