Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 15/20 | 1.00 |
| ▸ | CTSL | P07711 | 3/20 | 1.00 |
| ▸ | CTSB | P07858 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CTSG | P08311 | 1/20 | 1.00 |
| ▸ | CAPN9 | O14815 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aloxistatin SCHEMBL18498407 | 1.00 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL21981210 | 1.00 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL12620387 | 1.00 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL254426 | 1.00 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL483320 | 1.00 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL22273610 | 0.93 | CAPN1 (0.87) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL9314220 | 0.93 | CAPN1 (0.86) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL12653616 | 0.91 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL12653864 | 0.91 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL1804811 | 0.91 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165608-A1 | INHIBITION OF VASCULAR ENDOTHELIAL CELL-MEDIATED PHAGOCYTIC PROCESSES FOR TREATMENT OF DEMYELINATING CONDITIONS | NATIONAL SCIENCE FOUNDATION | 2020-05-28 | — | — | US | disclosed |