Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 16/20 | 0.86 |
| ▸ | CTSL | P07711 | 3/20 | 0.86 |
| ▸ | CTSB | P07858 | 3/20 | 0.86 |
| ▸ | LMNA | P02545 | 1/20 | 0.86 |
| ▸ | CTSG | P08311 | 1/20 | 0.86 |
| ▸ | CAPN9 | O14815 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aloxistatin SCHEMBL18498407 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL21981210 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL12620387 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL254426 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL483320 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| Aloxistatin SCHEMBL21981208 | 0.93 | CAPN1 (1.00) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL22273610 | 0.86 | CAPN1 (0.87) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL12653616 | 0.84 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL12653864 | 0.84 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL1804811 | 0.84 | CAPN1 (0.83) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298157-A | Mixing with acid and base; haet of reaction of hard acid with dimethylsulfide and base with boron trifluoride; extraction | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5296133-A | Extracting depolymerized coal with polar solvent to remove hard acid, soft base, minerals, mixing with swelling solvent so coal floats, minerals sink, separating | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5294349-A | Depolymerizing with a hard acid and soft base; catalytic hydrogenation using a precursor of a dihydrocarbyl metal dithiocarbamate | EXXON RESEARCH AND ENGINNERING COMPANY (US) | 1994-03-15 | — | — | US | disclosed |