SCHEMBL2198145

SCHEMBL2198145

CCCCCCCCC=CCCCCCCCC(=O)O[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 4/20 0.53
CNR2 P34972 1/20 0.47
TK2 O00142 2/20 0.46
SELP P16109 1/20 0.46
PRKCA P17252 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2198141 1.00 TLR4 (0.53) TLR4CNR2TK2SELPPRKCA
SCHEMBL2198149 1.00 TLR4 (0.53) TLR4CNR2TK2SELPPRKCA
SCHEMBL2309050 0.97 TLR4 (0.55) TLR4CNR2TK2
SCHEMBL2309054 0.97 TLR4 (0.55) TLR4CNR2TK2
SCHEMBL2309057 0.97 TLR4 (0.55) TLR4CNR2TK2
SCHEMBL2199753 0.93 TK2 (0.51) TLR4TK2PRKCA
SCHEMBL3791687 0.93 TK2 (0.51) TLR4TK2PRKCA
SCHEMBL2199758 0.93 TK2 (0.51) TLR4TK2PRKCA
SCHEMBL2200265 0.93 TK2 (0.51) TLR4TK2PRKCA
SCHEMBL2200260 0.93 TK2 (0.51) TLR4TK2PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 US claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 EP claimed
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2007-05-31 US claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US claimed
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP disclosed
US-8729254-B2 Derivative of glucose and vitamin F, compositions comprising it, uses and preparation process L'OREAL (FR) 2014-05-20 US disclosed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 EP disclosed
US-7977318-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2011-07-12 US disclosed
US-7795230-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-09-14 US disclosed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 US disclosed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 US disclosed
US-20060166902-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2006-07-27 US disclosed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP disclosed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO disclosed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US disclosed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060166902-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885CNR2 2644/4885TK2 861/4885
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885CNR2 2644/4885TK2 861/4885
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885CNR2 2644/4885TK2 861/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD TLR4 685/4885CNR2 2528/4885TK2 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.