SCHEMBL2198243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2198824	0.85	CDC7 (0.59)	CDC7PARP1BRD4CHEK1MAPK8
	SCHEMBL2200754	0.84	BRD4 (0.49)	CDC7BRD4
	SCHEMBL2201619	0.82	BRD4 (0.45)	CDC7PARP1BRD4
	SCHEMBL4355880	0.82	BRD4 (0.38)	CDC7BRD4CHEK1CSF1R
	SCHEMBL2198026	0.81	CDC7 (0.57)	CDC7CASP1CCNB2CDK1CCNB1
	SCHEMBL2197274	0.81	CDC7 (0.57)	CDC7BRD4CHEK1
	SCHEMBL2198480	0.81	NPC1 (0.46)	CDC7PARP1CASP1BRD4MAP2
	SCHEMBL12423887	0.81	BRD4 (0.59)	CDC7PARP1BRD4
	SCHEMBL2198095	0.81	CDC7 (0.57)	CDC7BRD4CHEK1CSF1R
	SCHEMBL12509725	0.81	BRD4 (0.44)	CDC7BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.