Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25316524 | 0.84 | — | — | |
| SCHEMBL1106086 | 0.78 | KCNH2 (0.33) | — | |
| SCHEMBL6904864 | 0.76 | — | — | |
| SCHEMBL2528825 | 0.73 | — | — | |
| SCHEMBL20734528 | 0.73 | — | — | |
| SCHEMBL11192096 | 0.71 | L3MBTL1 (0.32) | NOTUM | |
| SCHEMBL31532399 | 0.71 | NOTUM (0.30) | NOTUM | |
| SCHEMBL28114069 | 0.71 | CACNA1H (0.32) | NOTUM | |
| SCHEMBL21646570 | 0.71 | — | — | |
| SCHEMBL23515079 | 0.71 | NOTUM (0.32) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109504497-A | A kind of high-temperature anticorrosion renovation agent and preparation method thereof | 内蒙古三业科技开发有限公司 | 2019-03-22 | — | — | CN | claimed |
| EP-3867248-B1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-12-10 | — | — | EP | disclosed |
| US-12258327-B2 | 5-membered heteroaryl-containing aminopyridine compounds as EGFR inhibitors | YUHAN CORPORATION (KR) | 2025-03-25 | — | — | US | disclosed |
| US-20240246960-A1 | 7-Morpholino-L,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2024-07-25 | — | — | US | disclosed |
| EP-4305031-A1 | 7-MORPHOLINO-L,6-NAPHTHYRIDIN-5-YL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS DNA-PK INHIBITOR | Admare Therapeutics Society (CA) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022213204-A9 | CARBOXAMIDE PYROLOPYRAZINE AND PYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF MYT1 AND USE THEREOF IN THE TREATMENT OF CANCER | REPARE THERAPEUTICS INC. (CA) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023193114-A1 | METHODS OF USING ATR INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2023-10-12 | — | — | WO | disclosed |
| US-20230085912-A1 | 5-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2023-03-23 | — | — | US | disclosed |
| WO-2023027516-A1 | 5-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022261777-A1 | USE OF ATR INHIBITORS IN COMBINATION WITH PARP INHIBITORS FOR TREATING CANCER | REPARE THERAPEUTICS INC. (CA) | 2022-12-22 | — | — | WO | disclosed |
| US-20100063063-A1 | Substituted Heteroaryls | PFIZER INC | 2010-03-11 | — | — | US | disclosed |
| US-7396939-B2 | 3-cyclopropyl-4-(3-amino-2-methylbenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2008-07-08 | — | — | US | disclosed |
| US-7396939-B2 | 3-cyclopropyl-4-(3-amino-2-methylbenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2008-07-08 | — | — | US | disclosed |
| EP-1824338-B1 | 3-CYCLOPROPYL-4-(3-AMINO-2-METHYLBENZOYL)PYRAZOLS AND THE USE OF THE SAME AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| EP-1725103-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | Bayer CropScience GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005089551-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-09-29 | — | — | WO | disclosed |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230085912-A1 | 5-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | EGFR, ERBB2, ERBB4 | HSD11B1 4847/4885NOTUM 3618/4885 |
| US-20240246960-A1 | 7-Morpholino-L,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor | DCK, ERCC2, POLK | HSD11B1 4006/4885NOTUM 4721/4885 |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | CYP4X1, DDT, CYP4F3 | HSD11B1 3109/4885NOTUM 2837/4885 |
| US-12258327-B2 | 5-membered heteroaryl-containing aminopyridine compounds as EGFR inhibitors | EGFR, ERBB2, ERBB4 | HSD11B1 4847/4885NOTUM 3618/4885 |
| US-20100063063-A1 | Substituted Heteroaryls | GCKR, GCK, GALK1 | HSD11B1 498/4885NOTUM 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.