Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.71 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.71 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.71 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.71 |
| ▸ | CGAS | Q8N884 | 2/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.71 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | PRNP | P04156 | 2/20 | 0.59 |
| ▸ | MTOR | P42345 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292453 | 1.00 | LMNA (0.71) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292600 | 1.00 | LMNA (0.71) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL21983282 | 0.90 | LMNA (0.68) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292456 | 0.88 | LMNA (0.65) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292454 | 0.88 | LMNA (0.65) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292519 | 0.87 | LMNA (0.64) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292455 | 0.85 | LMNA (0.61) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL21982994 | 0.85 | LMNA (0.61) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL18292457 | 0.84 | LMNA (0.60) | LMNACHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL1612342 | 0.83 | CYP2D6 (0.67) | LMNACHRM2CHRM4CHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647677-B2 | Analogues of hydroxychloroquine (HCQ) without retinal toxicity | INOVIEM SCIENTIFIC (FR) | 2020-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647677-B2 | Analogues of hydroxychloroquine (HCQ) without retinal toxicity | SSB, UACA, XPA | LMNA 133/4885CHRM2 3788/4885CHRM4 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.