Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113226 | 0.90 | ALDH1A1 (0.50) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL7520399 | 0.87 | KMT2A (0.52) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| Hydrochloric Acid SCHEMBL28384994 | 0.85 | KMT2A (0.50) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL16750677 | 0.84 | LMNA (0.38) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL22736983 | 0.81 | ALDH1A1 (0.41) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL28164678 | 0.78 | ALDH1A1 (0.61) | LMNAALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL6263445 | 0.78 | ALDH1A1 (0.43) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL10629764 | 0.76 | LMNA (0.56) | LMNAALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL26971247 | 0.76 | LMNA (0.52) | LMNASLC15A2ALDH1A1CYP1A2THRB | |
| SCHEMBL3838466 | 0.75 | THRB (0.46) | LMNAALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10648026-B2 | Raman cluster tagged molecules for biological imaging | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-05-12 | — | — | US | disclosed |