SCHEMBL2198447

SCHEMBL2198447

C[Si](Cl)(O[Si](C)(Cl)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
TSHR P16473 4/20 0.33
ALDH1A1 P00352 2/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TP53 P04637 1/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 2/20 0.31
AOC3 Q16853 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ORAI1 Q96D31 1/20 0.31
ORAI2 Q96SN7 1/20 0.31
ORAI3 Q9BRQ5 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
HSP90AA1 P07900 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951085 0.89 ESR1 (0.33) ESR1ESR2TSHR
SCHEMBL28355526 0.88 ESR1 (0.35) ESR1ESR2TSHRALDH1A1
SCHEMBL9766282 0.83 ESR1 (0.32) ESR1ESR2
SCHEMBL4195240 0.82 ESR1 (0.38) ESR1ESR2TSHRALDH1A1NR1H2
SCHEMBL11034567 0.80 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL1130763 0.78 CA4 (0.39) ESR1ESR2TSHRCA4
SCHEMBL9814455 0.78
SCHEMBL9633287 0.77 ESR1 (0.34) ESR1ESR2TSHRALDH1A1TP53
SCHEMBL21923149 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL19755901 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106343-A1 ETCHING METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-05-22 WO claimed
US-20250157825-A1 ETCHING METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2025-05-15 US claimed
US-20240258111-A1 Surface Treatment Compositions and Methods FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-08-01 US claimed
CN-117069443-A High-strength baking-free brick prepared from construction waste and preparation method thereof 浙江博世华环保科技有限公司 2023-11-17 CN claimed
CN-111565859-B Surface treatment composition and method 富士胶片电子材料美国有限公司 2022-12-30 CN claimed
US-11447642-B2 Methods of using surface treatment compositions FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2022-09-20 US claimed
US-11174394-B2 Surface treatment compositions and articles containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2021-11-16 US claimed
US-20210122925-A1 METHODS OF USING SURFACE TREATMENT COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2021-04-29 US claimed
CN-112513192-A Surface treatment composition and method 富士胶片电子材料美国有限公司 2021-03-16 CN claimed
CN-111565859-A Surface treatment composition and method 富士胶片电子材料美国有限公司 2020-08-21 CN claimed
US-20060281934-A1 Processes for the production of polycyclic fused ring compounds FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20060281933-A1 Processes for the preparation of paclitaxel FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20060281932-A1 Processes for the preparation of docetaxel FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-12-14 US claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
EP-0799852-B1 Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING (US) 2003-09-24 EP claimed
EP-1006136-A1 Solid-liquid phase interfacial polymerisation DOW CORNING CORPORATION (US) 2000-06-07 EP claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799852-A2 Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5637668-A REACTING DIHALOSILOXANE COMPOUND AND ORGANOSILANOLATE AT INTERFACE OF TWO NONAQUEOUS SOLVENTS IMMISCIBLE IN EACH OTHER DOW CORNING CORPORATION (US) 1997-06-10 US claimed
US-5126419-A Light-sensitive polymer, method for preparing the same andmethod for forming patterns MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-06-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281934-A1 Processes for the production of polycyclic fused ring compounds COASY, PARG, PIN4 ESR1 2925/4885ESR2 2851/4885TSHR 4755/4885
US-20060281933-A1 Processes for the preparation of paclitaxel PDCD10, PDS5B, CASP10 ESR1 3811/4885ESR2 3752/4885TSHR 4488/4885
US-20060281932-A1 Processes for the preparation of docetaxel PDCD10, PDS5B, DHCR7 ESR1 2475/4885ESR2 2470/4885TSHR 4027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.