Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | PNMT | P11086 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21984962 | 0.85 | GPR119 (0.39) | HTR2CHTR2AMAPK1SLC6A2SLC6A4 | |
| SCHEMBL19409649 | 0.75 | HTR2C (0.38) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL19030789 | 0.73 | HIF1A (0.36) | HTR2CHTR2A | |
| SCHEMBL21984765 | 0.71 | GPR119 (0.39) | SLC6A2SLC6A4MEN1KMT2ATMEM97 | |
| SCHEMBL19409506 | 0.70 | MGLL (0.54) | — | |
| SCHEMBL19409508 | 0.70 | MGLL (0.54) | — | |
| SCHEMBL15075072 | 0.66 | TRPV1 (0.39) | HTR2CHTR2AHTR2B | |
| SCHEMBL27837691 | 0.64 | TDP2 (0.43) | — | |
| SCHEMBL4243005 | 0.64 | HTR2C (0.45) | HTR2CSLC6A2SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31136299 | 0.63 | HTR2A (0.34) | HTR2CHTR2AHTR2BPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436444-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-05-13 | — | — | EP | disclosed |