Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22662071 | 0.87 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL21988022 | 0.74 | LMNA (0.35) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL20641545 | 0.73 | LMNA (0.41) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL19963118 | 0.72 | GAA (0.39) | CYP3A4CYP2C9CYP2B6CYP2C19HTT | |
| SCHEMBL20544294 | 0.71 | CYP3A4 (0.34) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL19963087 | 0.70 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL29594970 | 0.70 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL5225657 | 0.63 | NOTUM (0.48) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL8132461 | 0.62 | HTT (0.43) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA | |
| SCHEMBL8232133 | 0.62 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2B6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836734-B2 | Spiroquinone derivative compound, production method thereof, and pharamaceutical composition for preventing or treating neurological disorders which contains same as active ingredient | GACHON UNIVERSITY OF INDUSTRY—ACADEMIC COOPERATION FOUNDATION (KR) | 2020-11-17 | — | — | US | disclosed |
| EP-3395804-B1 | NOVEL SPIROQUINONE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS WHICH CONTAINS SAME AS ACTIVE INGREDIENT | UNIV GACHON IND ACAD COOP FOUND (KR) | 2020-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836734-B2 | Spiroquinone derivative compound, production method thereof, and pharamaceutical composition for preventing or treating neurological disorders which contains same as active ingredient | NQO1, SDHA, SDHB | CYP3A4 701/4885CYP2C9 447/4885CYP2B6 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.