SCHEMBL21986176

SCHEMBL21986176

Cc1cc2c(cn1)CC(C)CN(N)C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909845 0.77 CHRNA7 (0.38) UHRF1CHRNA7
SCHEMBL14525626 0.71 CHRNA7 (0.44) UHRF1CHRNA7
SCHEMBL16181319 0.66 UHRF1 (0.35) UHRF1CHRNA7
SCHEMBL24065186 0.65 CHRNA7 (0.37) UHRF1CHRNA7
SCHEMBL25045623 0.65 HDAC1 (0.36) UHRF1CHRNA7
SCHEMBL13291936 0.62 FYN (0.36) UHRF1CHRNA7
SCHEMBL19498204 0.62 CYP1A2 (0.35) UHRF1CHRNA7
SCHEMBL30142971 0.62 HDAC1 (0.46) UHRF1
SCHEMBL21205774 0.61 NOS3 (0.50)
SCHEMBL21205776 0.61 CHRNB2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172214-B1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2020-05-13 EP disclosed