⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605419 | 0.78 | — | — | |
| SCHEMBL15238182 | 0.78 | — | — | |
| SCHEMBL21986229 | 0.75 | DPP4 (0.43) | — | |
| SCHEMBL2744920 | 0.75 | PREP (0.37) | — | |
| SCHEMBL23598744 | 0.74 | DPP4 (0.43) | — | |
| SCHEMBL26999725 | 0.74 | PREP (0.42) | — | |
| SCHEMBL5728068 | 0.74 | DPP4 (0.40) | — | |
| SCHEMBL2605420 | 0.72 | DPP4 (0.42) | — | |
| SCHEMBL28056504 | 0.72 | DPP4 (0.46) | — | |
| SCHEMBL5140895 | 0.71 | DPP4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038406-A2 | NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF | National Research Council of Canada (CA) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008020333-A2 | NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF | NATIONAL RESEARCH COUNCIL OF CANADA (US) | 2008-02-21 | — | — | WO | disclosed |