Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.31 |
| ▸ | UGCG | Q16739 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18747986 | 0.85 | ALOX15 (0.36) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL18666649 | 0.83 | BRD4 (0.35) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL9934296 | 0.82 | BRD4 (0.40) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL24675784 | 0.81 | BRD4 (0.35) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL9935368 | 0.77 | UGCG (0.39) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL9934235 | 0.77 | UGCG (0.39) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL7952458 | 0.77 | IDH1 (0.46) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL20870730 | 0.76 | — | — | |
| SCHEMBL7911235 | 0.76 | KDM4E (0.38) | BRD4TNFIL1BIKZF1DDB1 | |
| SCHEMBL15247750 | 0.75 | KDM4E (0.44) | BRD4TNFIL1BIKZF1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135275-B1 | PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS | GRINDEKS JSC (LV) | 2020-05-13 | — | — | EP | disclosed |