Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15918975 | 0.79 | PDE10A (0.36) | L3MBTL1IKBKB | |
| SCHEMBL2180713 | 0.78 | SSTR4 (0.32) | L3MBTL1IKBKB | |
| SCHEMBL2180681 | 0.76 | GRIN2D (0.33) | L3MBTL1IKBKB | |
| SCHEMBL2480217 | 0.76 | NUDT1 (0.47) | — | |
| SCHEMBL14381040 | 0.75 | TLR7 (0.33) | — | |
| SCHEMBL20382914 | 0.73 | TLR7 (0.33) | — | |
| SCHEMBL15061729 | 0.72 | TLR7 (0.32) | — | |
| SCHEMBL8240168 | 0.72 | CSNK1E (0.33) | L3MBTL1 | |
| SCHEMBL8240025 | 0.72 | TLR7 (0.53) | — | |
| SCHEMBL19554107 | 0.71 | MYC (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |