Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.45 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240025 | 0.92 | TLR7 (0.53) | NUDT1TLR7AHCYADORA3 | |
| SCHEMBL15918975 | 0.79 | PDE10A (0.36) | NUDT1TLR7 | |
| SCHEMBL2180713 | 0.78 | SSTR4 (0.32) | NUDT1 | |
| SCHEMBL13954583 | 0.76 | NUDT1 (0.47) | NUDT1TLR7AHCYADORA3 | |
| SCHEMBL21986320 | 0.76 | L3MBTL1 (0.34) | — | |
| SCHEMBL2180681 | 0.76 | GRIN2D (0.33) | — | |
| SCHEMBL1674116 | 0.76 | NUDT1 (0.47) | NUDT1TLR7AHCYADORA3 | |
| SCHEMBL14381040 | 0.75 | TLR7 (0.33) | TLR7ADORA3 | |
| SCHEMBL20382914 | 0.73 | TLR7 (0.33) | TLR7AHCY | |
| SCHEMBL23351005 | 0.72 | NUDT1 (0.38) | NUDT1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373169-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | Gilead Connecticut, Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010068257-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | disclosed |