SCHEMBL21987682

SCHEMBL21987682

NC(=O)N([SH](=O)=O)[SH](=O)=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.33
OR51E2 Q9H255 1/20 0.33
CRBN Q96SW2 1/20 0.33
ACHE P22303 1/20 0.31
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27457811 0.71 LMNA (0.38) LMNAALOX15BLMPMP22TDP1
SCHEMBL28739406 0.69
SCHEMBL27344258 0.69
SCHEMBL26659497 0.69
SCHEMBL27827692 0.67 LMNA (0.36) LMNAALOX15BLMPMP22
SCHEMBL75527 0.65
SCHEMBL27985624 0.65 ALDH1A1 (0.47) LMNAALOX15BLMPMP22TDP1
SCHEMBL27625919 0.65
SCHEMBL21811 0.65
SCHEMBL9157892 0.62 LMNA (0.43) LMNAALOX15BLMPMP22TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2024-03-12 US disclosed
CN-111747872-A Synthetic method of p-toluenesulfonylurea 江苏理工学院 2020-10-09 CN disclosed
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-06-04 US disclosed
CN-107427010-A LIQUID SULFONYLUREA-CONTAINING HERBICIDAL COMPOSITIONS 三井农业化学国际有限公司 2017-12-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL TDO2, SCO2, SCN1A LMNA 3571/4885ALOX15 2876/4885BLM 4083/4885
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material TDO2, SCO2, SCN1A LMNA 3530/4885ALOX15 2915/4885BLM 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.