Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199802 | 0.91 | ADORA2A (0.43) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL2199789 | 0.85 | ADORA2A (0.44) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL4553782 | 0.85 | ADORA2A (0.44) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL10057869 | 0.85 | ADORA2A (0.37) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL2199084 | 0.82 | TLR7 (0.37) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL29809327 | 0.81 | TLR7 (0.47) | ADORA2AADORA2BTLR7 | |
| SCHEMBL567233 | 0.81 | TLR7 (0.47) | ADORA2AADORA2BTLR7 | |
| SCHEMBL2200726 | 0.81 | TLR7 (0.41) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL2486847 | 0.80 | TLR7 (0.47) | ADORA2AADORA2BTLR7 | |
| SCHEMBL31124759 | 0.80 | ADORA2A (0.40) | ADORA2AADORA2BADORA3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977344-B2 | Compounds | GLAXOSMITHKLINE LLC (US) | 2011-07-12 | — | — | US | disclosed |
| US-20090131458-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131458-A1 | Compounds | LTC4S, LTB4R2, LTB4R | ADORA2A 907/4885ADORA2B 494/4885ADORA3 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.