Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34413 | 0.81 | IDO1 (0.67) | IDO1AGXTCA1CA2APP | |
| SCHEMBL3803477 | 0.81 | IDO1 (0.52) | IDO1AGXTCA1CA2APP | |
| SCHEMBL25621739 | 0.80 | CYP2A6 (0.48) | ALDH1A1TAAR1 | |
| SCHEMBL13232449 | 0.80 | AGXT (0.48) | IDO1AGXTCA1CA2L3MBTL1 | |
| SCHEMBL20213990 | 0.79 | IDO1 (0.50) | IDO1AGXTCA1CA2APP | |
| Potassium SCHEMBL1477050 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP | |
| Hydrochloric Acid SCHEMBL28912134 | 0.79 | IDO1 (0.68) | IDO1AGXTCA1CA2APP | |
| Methoxymethane SCHEMBL28823290 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP | |
| Bromide SCHEMBL28558295 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP | |
| SCHEMBL1475481 | 0.79 | IDO1 (0.64) | IDO1AGXTCA1CA2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12103921-B2 | Chemical compounds | PFIZER INC. (US) | 2024-10-01 | — | — | US | disclosed |
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-116370650-B | Tetrazine linker-based polypeptide drug conjugate and preparation method and application thereof | 四川大学华西医院 | 2024-03-22 | — | — | CN | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| CN-116370650-A | Tetrazine linker-based polypeptide drug conjugate and preparation method and application thereof | 四川大学华西医院 | 2023-07-04 | — | — | CN | disclosed |
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |
| US-20220348555-A1 | Chemical Compounds | PFIZER INC. (US) | 2022-11-03 | — | — | US | disclosed |
| EP-3886984-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | Pfizer Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2020109994-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | PFIZER INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109994-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | PFIZER INC. (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
| US-12103921-B2 | Chemical compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
| US-20220348555-A1 | Chemical Compounds | HBZ, HBB, HBS1L | IDO1 2827/4885AGXT 1822/4885CA1 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.