SCHEMBL2198949

SCHEMBL2198949

C[Si](C)(Cl)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)Cl

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962546 1.00 ALDH1A1 (0.36) ALDH1A1
SCHEMBL523534 1.00 ALDH1A1 (0.36) ALDH1A1
SCHEMBL297263 0.96 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9930113 0.90
SCHEMBL22264581 0.90
SCHEMBL8846171 0.90
SCHEMBL19145978 0.86 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8846179 0.86 ALDH1A1 (0.31) ALDH1A1
SCHEMBL22264587 0.83
SCHEMBL21373939 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025031589-A1 PHENOL-TERMINATED SILOXANES WACKER CHEMIE AG (DE) 2025-02-13 WO disclosed
EP-1719794-B1 NOVEL POLYMERS AND USES THEREOF MITSUI CHEMICALS INC (JP) 2017-01-04 EP disclosed
EP-2580255-B1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES US GOV SEC NAVY (US) 2016-09-07 EP disclosed
US-8440850-B2 Polyarylacetylenes containing siloxane, silane, and carborane moieties THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-05-14 US disclosed
EP-2580255-A2 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES The Government of the United States of America as represented by the Secretary of the Navy (US) 2013-04-17 EP disclosed
US-8269030-B2 Polyarylacetylenes containing siloxane, silane, and carborane moieties THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-09-18 US disclosed
US-20120190808-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-07-26 US disclosed
US-20120184699-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES The Government of the United State of America, as represented by the Secretary of the Navy (US) 2012-07-19 US disclosed
US-8217194-B2 Polyarylacetylenes containing siloxane, silane, and carborane moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-07-10 US disclosed
WO-2011156678-A2 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-12-15 WO disclosed
US-20110306744-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-12-15 US disclosed
US-7977429-B2 Polymers and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-07-12 US disclosed
US-20070154431-A1 Novel polymers and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-07-05 US disclosed
EP-1719794-A1 NOVEL POLYMERS AND USES THEREOF Mitsui Takeda Chemicals, Inc. (JP) 2006-11-08 EP disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306744-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES SIRT2, SUMO2, MCM2 ALDH1A1 3215/4885
US-20070154431-A1 Novel polymers and uses thereof RAD54L, VCL, TYR ALDH1A1 3272/4885
US-20120190808-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES SIRT2, SUMO2, MCM2 ALDH1A1 3588/4885
US-20120184699-A1 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES SIRT2, SUMO2, MCM2 ALDH1A1 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.