SCHEMBL21990559

SCHEMBL21990559

C=Cc1ccccc1S(=O)(=O)NCC(=C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 7/20 0.48
▸ CA9 Q16790 7/20 0.48
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ GBA1 P04062 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ MMP1 P03956 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MMP12 P39900 1/20 0.33
▸ MEP1B Q16820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16831931 0.78 RECQL (0.54) CA12CA9CA1CA2ALDH1A1
SCHEMBL7525621 0.75 CYP1A2 (0.44) CA12CA9CA1CA2ALDH1A1
SCHEMBL27393985 0.74 RECQL (0.42) CA12CA9KDM4EALDH1A1RECQL
SCHEMBL7784368 0.74 CA1 (0.70) CA12CA9CA1CA2GBA1
SCHEMBL10350064 0.73 TDP1 (0.35) ALDH1A1
SCHEMBL10870064 0.72 ALDH1A1 (0.38) CA12CA9CA1CA2GBA1
SCHEMBL21540192 0.71 CA12 (0.46) CA12CA9CA1CA2KDM4E
SCHEMBL20267704 0.71 CA12 (0.46) CA12CA9CA1CA2ALDH1A1
SCHEMBL11539283 0.70 MEN1 (0.40) CA9CA1CA2ALDH1A1MMP1
SCHEMBL9567510 0.69 ALDH1A1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666753-B1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORP (JP) 2024-09-11 — — EP disclosed
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof TOSOH FINECHEM CORPORATION (JP) 2022-10-04 — — US disclosed
EP-3666753-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF Tosoh Finechem Corporation (JP) 2020-06-17 — — EP disclosed
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORPORATION (JP) 2020-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof SLC7A1, ARSA, STS CA12 3159/4885CA9 2904/4885CA1 3904/4885
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF SLC7A1, ARSA, STS CA12 3159/4885CA9 2904/4885CA1 3904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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