Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798389 | 0.82 | LMNA (0.46) | CYP1A2ALDH1A1NR3C2L3MBTL1LMNA | |
| SCHEMBL10870064 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL4731653 | 0.79 | CYP1A2 (0.55) | CYP1A2ALDH1A1NR3C2L3MBTL1LMNA | |
| SCHEMBL9567510 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRHTT | |
| SCHEMBL1396538 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRGAACA12 | |
| SCHEMBL13232803 | 0.77 | TSHR (0.58) | CYP1A2ALDH1A1NR3C2LMNATSHR | |
| SCHEMBL10594900 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRGAACA12 | |
| SCHEMBL13232799 | 0.75 | CYP1A2 (0.40) | CYP1A2ALDH1A1NR3C2L3MBTL1LMNA | |
| SCHEMBL11539283 | 0.75 | MEN1 (0.40) | ALDH1A1CA1CA2CA5ACA9 | |
| SCHEMBL21990559 | 0.75 | CA12 (0.48) | ALDH1A1GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014979-A9 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR KRAS G12C PROTEINS | RAYZEBIO, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023014988-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS | RAYZEBIO, INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023014979-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR KRAS G12C PROTEINS | RAYZEBIO, INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-1207360-C | High solids acid etch and resistant clear coating composition | DU PONT (US) | 2005-06-22 | — | — | CN | disclosed |
| EP-0855267-B1 | Planographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2002-04-17 | — | — | EP | disclosed |
| CN-1343238-A | High-solid acid-corrosion-resistant scratch-resistant transparent coating composition | DU PONT (US) | 2002-04-03 | — | — | CN | disclosed |
| US-6017677-A | SUBSTRATE HAVING RCORDING LAYER CONTAINING PHOTO ACID-GENERATING AGENT AND A POLYMER HAVING SULFONIC ACID-GENERATING MOIETIES ON SIDE CHAINS | FUJI PHOTO FILM CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0855267-A2 | Planographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-3980713-A | FLUORESCENT BRIGHTENERS | NIPPON KAYAKU CO., LTD. (JA) | 1976-09-14 | — | — | US | disclosed |