SCHEMBL21990816

SCHEMBL21990816

In1cc2c(n1)CNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19042347 0.82 POLB (0.39)
Hydrochloric Acid SCHEMBL2750120 0.72 SOD3 (0.34)
SCHEMBL18806203 0.71 AADAT (0.36)
SCHEMBL18806097 0.69 PDK2 (0.38)
SCHEMBL30970615 0.69 AADAT (0.33)
SCHEMBL31652215 0.69 HTR2C (0.34)
SCHEMBL15203113 0.67
SCHEMBL17214083 0.67 AADAT (0.37)
SCHEMBL12478204 0.67 PTGS2 (0.39)
SCHEMBL12182132 0.67 POLB (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172214-B1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2020-05-13 EP disclosed