Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668199 | 1.00 | MEN1 (0.50) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL5550758 | 0.97 | MEN1 (0.46) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL11250542 | 0.86 | ALOX15 (0.38) | KMT2AALDH1A1LMNA | |
| SCHEMBL10510078 | 0.82 | HRH3 (0.49) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL1455583 | 0.82 | HRH3 (0.49) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL7769335 | 0.82 | HRH3 (0.52) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL6262966 | 0.80 | MEN1 (0.46) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| Hydroxyamine SCHEMBL1454400 | 0.80 | L3MBTL1 (0.50) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL10451646 | 0.80 | MAPT (0.46) | MEN1KMT2AHRH3MAPTALDH1A1 | |
| SCHEMBL3271095 | 0.79 | HRH3 (0.46) | MEN1KMT2AHRH3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201205-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |