Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550119 | 0.82 | PDE2A (0.41) | TSHRPDE2A | |
| SCHEMBL12401849 | 0.75 | POLB (0.46) | TSHR | |
| SCHEMBL9723054 | 0.75 | TSHR (0.36) | TSHRARPDE2A | |
| SCHEMBL22927054 | 0.73 | PTPN5 (0.35) | TSHR | |
| SCHEMBL8321562 | 0.72 | PDE2A (0.44) | TSHRPDE2A | |
| SCHEMBL2006163 | 0.70 | POLB (0.52) | TSHR | |
| SCHEMBL10493701 | 0.69 | TSHR (0.50) | TSHR | |
| SCHEMBL10687193 | 0.68 | TSHR (0.62) | TSHRARPDE2A | |
| SCHEMBL9140039 | 0.67 | PGK1 (0.31) | — | |
| SCHEMBL1830038 | 0.67 | RAPGEF4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981524-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |