Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22056591 | 0.67 | — | — | |
| SCHEMBL14767651 | 0.57 | TRPA1 (0.30) | — | |
| SCHEMBL13896927 | 0.56 | NPC1 (0.47) | — | |
| SCHEMBL25020455 | 0.56 | — | — | |
| SCHEMBL22781002 | 0.56 | — | — | |
| SCHEMBL13090814 | 0.54 | L3MBTL1 (0.33) | — | |
| SCHEMBL17733614 | 0.54 | L3MBTL1 (0.33) | — | |
| SCHEMBL19216876 | 0.53 | KIF11 (0.31) | — | |
| SCHEMBL14516394 | 0.53 | — | — | |
| SCHEMBL1270189 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |