Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 3/20 | 0.42 |
| ▸ | KDM5C | P41229 | 3/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21991179 | 0.77 | KCNQ3 (0.48) | MAPTGSK3BGSK3ANPC1RAB9A | |
| SCHEMBL21990942 | 0.75 | GSK3B (0.32) | GSK3B | |
| SCHEMBL23020847 | 0.75 | KDM4D (0.47) | KDM4DKDM4CKDM4EKDM6BKDM5C | |
| SCHEMBL24473804 | 0.74 | HCAR3 (0.61) | KDM4DKDM4CKDM4EKDM6BKDM5C | |
| SCHEMBL2714358 | 0.73 | ACVRL1 (0.62) | MAPTGSK3BGSK3A | |
| SCHEMBL21991148 | 0.73 | GRM4 (0.50) | MAPTGSK3BGSK3A | |
| SCHEMBL21014454 | 0.72 | L3MBTL1 (0.45) | KDM4EALDH1A1MAPTGSK3BGSK3A | |
| SCHEMBL23304365 | 0.72 | HCAR3 (0.63) | KDM4DKDM4CKDM4EKDM6BKDM5C | |
| SCHEMBL23021195 | 0.72 | KDM4D (0.49) | KDM4DKDM4CKDM4EKDM6BKDM5C | |
| SCHEMBL30260126 | 0.72 | HCAR3 (0.63) | KDM4DKDM4CKDM4EKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |