Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21991038 | 0.95 | ALDH1A1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21991156 | 0.89 | GRM4 (0.42) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21990941 | 0.87 | L3MBTL1 (0.47) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL19380323 | 0.86 | ALDH1A1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21991040 | 0.85 | L3MBTL1 (0.45) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL17880510 | 0.84 | MAPK14 (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21991042 | 0.83 | SMN1; SMN2 (0.47) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21990943 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21990938 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL21991143 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |