Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21991736 | 0.93 | CCR2 (0.47) | L3MBTL1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL21014454 | 0.91 | L3MBTL1 (0.45) | L3MBTL1NPC1RAB9ANPSR1KCNQ3 | |
| SCHEMBL21014612 | 0.89 | NPC1 (0.43) | L3MBTL1NPC1RAB9ANPSR1KCNQ3 | |
| SCHEMBL21991185 | 0.88 | KCNQ3 (0.44) | L3MBTL1NPC1RAB9ANPSR1KCNQ3 | |
| SCHEMBL21991038 | 0.87 | ALDH1A1 (0.46) | L3MBTL1NPC1RAB9ANPSR1KCNQ3 | |
| SCHEMBL21991179 | 0.86 | KCNQ3 (0.48) | NPC1RAB9AKCNQ3KCNQ2KCNE1 | |
| SCHEMBL21991737 | 0.83 | L3MBTL1 (0.47) | L3MBTL1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL21014410 | 0.83 | MAOB (0.45) | NPC1RAB9AKCNQ3KCNQ2MAOB | |
| SCHEMBL21991183 | 0.83 | NPC1 (0.52) | L3MBTL1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL21991148 | 0.81 | GRM4 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |