Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA4 | P51532 | 6/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | NME2 | P22392 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993751 | 0.84 | SMARCA4 (0.60) | SMARCA4PBRM1MEN1KMT2ANME2 | |
| SCHEMBL21992948 | 0.81 | SMARCA4 (0.48) | SMARCA4PBRM1MEN1KMT2ANME2 | |
| SCHEMBL21993749 | 0.81 | SMARCA4 (0.48) | SMARCA4PBRM1MEN1KMT2ANME2 | |
| SCHEMBL21992960 | 0.78 | SMARCA4 (0.60) | SMARCA4PBRM1MEN1KMT2A | |
| SCHEMBL21992771 | 0.78 | PBRM1 (0.64) | SMARCA4PBRM1 | |
| SCHEMBL21993752 | 0.77 | SMARCA4 (0.56) | SMARCA4PBRM1MEN1KMT2A | |
| SCHEMBL21992747 | 0.76 | SMARCA4 (0.58) | SMARCA4PBRM1 | |
| SCHEMBL21993276 | 0.74 | SMARCA4 (0.64) | SMARCA4PBRM1MEN1KMT2A | |
| SCHEMBL21931879 | 0.74 | SMARCA4 (0.60) | SMARCA4PBRM1MEN1KMT2ANME2 | |
| SCHEMBL21931884 | 0.74 | SMARCA4 (0.60) | SMARCA4PBRM1MEN1KMT2ANME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | GALECTIN SCIENCES, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | LGALS1, LGALS2, LGALS3 | SMARCA4 4569/4885PBRM1 4399/4885MEN1 523/4885 |
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | LGALS1, LGALS2, LGALS3 | SMARCA4 4569/4885PBRM1 4399/4885MEN1 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.