SCHEMBL21993749

SCHEMBL21993749

O=c1nc2n(c3ccccc13)CC/C2=C\c1ccc(CS(=O)(=O)c2ccc(F)c(F)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SMARCA4 P51532 6/20 0.48
▸ PBRM1 Q86U86 3/20 0.48
▸ BLM P54132 3/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ NME2 P22392 4/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859440 0.87 SMARCA4 (0.52) SMARCA4PBRM1MEN1KMT2ANPC1
SCHEMBL20704901 0.87 SMARCA4 (0.52) SMARCA4PBRM1MEN1KMT2ANPC1
SCHEMBL21993751 0.84 SMARCA4 (0.60) SMARCA4PBRM1MEN1KMT2ANPC1
SCHEMBL21993752 0.82 SMARCA4 (0.56) SMARCA4PBRM1MEN1KMT2ANPC1
SCHEMBL21992948 0.81 SMARCA4 (0.48) SMARCA4PBRM1BLMMEN1KMT2A
SCHEMBL21992757 0.81 SMARCA4 (0.48) SMARCA4PBRM1MEN1KMT2ANME2
SCHEMBL21992771 0.78 PBRM1 (0.64) SMARCA4PBRM1BLMNPC1RAB9A
SCHEMBL21992960 0.78 SMARCA4 (0.60) SMARCA4PBRM1BLMMEN1KMT2A
SCHEMBL21992747 0.76 SMARCA4 (0.58) SMARCA4PBRM1BLMNPC1RAB9A
SCHEMBL30139674 0.75 SMARCA4 (0.57) SMARCA4PBRM1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885BLM 1148/4885
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885BLM 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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